C-type Lectin Receptors: Signaling and Therapeutic Opportunities
نویسندگان
چکیده
منابع مشابه
Signaling C-type lectin receptors in antimycobacterial immunity
The mammalian innate immune system is composed of phagocytes such as macrophages and dendritic cells that serve as the first line of defense against microbial infections. These cells express various pattern recognition receptors (PRRs) that recognize specific pathogen-associated molecular patterns (PAMPs) on the surface of or inside microorganisms [1]. PRRs such as Toll-like receptors (TLRs), C...
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C-type lectin receptors (CLRs) are important pattern recognition receptors involved in recognition and induction of adaptive immunity to pathogens. Certain CLRs play an important role in viral infections as they efficiently interact with viruses. However, it has become clear that deadly viruses subvert the function of CLRs to escape antiviral immunity and promote infection. In particular, virus...
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ژورنال
عنوان ژورنال: Arzneimittelforschung
سال: 2012
ISSN: 0004-4172,1616-7066
DOI: 10.1055/s-0032-1324910